Separase

Separase

Separase ist ein Enzym.

Es baut die Cohesine ab, die die Schwesterchromatiden in der Mitose zusammenhalten und ermöglicht so die Segregation des genetischen Materials in der Mitose.

Literatur

  • Diplom-Biologe Dominik Boos (März 2007): Separase: Regulation, Funktion und neue Substrate (PDF). Dissertation der Fakultät für Biologie der Ludwig-Maximilians-Universität München. Abgerufen am 18. Mai 2009.
  • National Library of Medicine - Medical Subject Headings (MeSH): separase, hier online

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  • Separase — protein Name=extra spindle pole bodies homolog 1 (S. cerevisiae) caption= width= HGNCid=16856 Symbol=ESPL1 AltSymbols= EntrezGene=9700 OMIM=604143 RefSeq=NM 012291 UniProt=Q14674 PDB= ECnumber=3.4.22.49 Chromosome=12 Arm=q Band=13.13… …   Wikipedia

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  • Securin — Protbox topfields|Gene= [http://www.ncbi.nih.gov/entrez/query.fcgi?db=nucleotide cmd=search term=U12185 doptcmdl=GenBank] #ID : AAB00106.1 Structure=Unknown|Review= [http://www.ncbi.nih.gov/entrez/query.fcgi?cmd=Retrieve db=PubMed list… …   Wikipedia

  • Anaphase — Anaphase, from the ancient Greek ἀνά (up) and φάσις (stage), is the stage of mitosis when chromosomes separate in a eukaryotic cell. Each chromatid moves to opposite poles of the cell, the opposite ends of the mitotic spindle, near the… …   Wikipedia

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  • RAD21 — homolog (S. pombe), also known as RAD21, is a human gene.cite web | title = Entrez Gene: RAD21 RAD21 homolog (S. pombe)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5885| accessdate = ] PBB Summary… …   Wikipedia

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  • securin — se·cu·rin (sə kūrґin) a protease inhibitor that binds separase; its degradation releases separase to cleave cohesin and initiate chromatid separation in anaphase. Securin is overexpressed in some pituitary tumors and can act as an… …   Medical dictionary

  • separar — Se conjuga como: amar Infinitivo: Gerundio: Participio: separar separando separado     Indicativo   presente imperfecto pretérito futuro condicional yo tú él, ella, Ud. nosotros vosotros ellos, ellas, Uds. separo separas separa separamos separáis …   Wordreference Spanish Conjugations Dictionary

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