Lymphotoxin

Lymphotoxin
Struktur des Lymphotoxin-α-Trimer mit einem TNF-Rezeptor-Trimer.[1]

Lymphotoxin-α (kurz LTA, alternativ auch Tumornekrosefaktor-β, kurz TNFB, oder ganz wissenschaftlich Tumor necrosis factor ligand superfamily member 1, kurz TNFSF1) ist ein Zytokin aus der TNF/TNFR-Superfamilie. Es hat viele Gemeinsamkeiten mit TNF – teilt z. B. dessen Rezeptoren – wird aber von aktivierten Lymphozyten sezerniert. Es ist wie TNF ein Modulator der Immunantwort.

Quellen

  1. Swiss-3DIMAGE:P01374

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Schlagen Sie auch in anderen Wörterbüchern nach:

  • Lymphotoxin-α — Bändermodell des LTA:TNF Rezeptor Komplexes (Monomer) nach PDB  …   Deutsch Wikipedia

  • Lymphotoxin — protein Name = lymphotoxin alpha (TNF superfamily, member 1) caption = width = HGNCid = 6709 Symbol = LTA AltSymbols = TNFB EntrezGene = 4049 OMIM = 153440 RefSeq = NM 000595 UniProt = P01374 PDB = ECnumber = Chromosome = 6 Arm = p Band = 21.3… …   Wikipedia

  • lymphotoxin — Cytotoxic product of T cells: the term is usually restricted to tumour necrosis factor b which is also known as lymphotoxin …   Dictionary of molecular biology

  • Lymphotoxin beta receptor — is a receptor for lymphotoxin. PBB Summary section title = summary text = The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of… …   Wikipedia

  • Lymphotoxin alpha — (TNF superfamily, member 1), also known as LTA, is a human gene. PBB Summary section title = summary text = Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted …   Wikipedia

  • lymphotoxin — /lim feuh tok sin/, n. Immunol. a glycoprotein that is released by antigen stimulated or mitogen stimulated T cells and is toxic to various other cells. [1970 75; LYMPHO + TOXIN] * * * …   Universalium

  • lymphotoxin — noun Any of several lymphokines that are toxic to certain cells …   Wiktionary

  • lymphotoxin — A lymphokine from T lymphocytes that lyses or damages many cell types. * * * lym·pho·tox·in .lim(p) fō täk sən n a lymphokine that lyses various cells and esp. tumor cells lym·pho·tox·ic täk sik adj * * * lym·pho·tox·in (LT) (limґfo… …   Medical dictionary

  • Lymphotoxin — Lỵm|pho|to|xin [↑ Lymphe u. ↑ Toxin] ↑ Tumor Nekrose Faktor …   Universal-Lexikon

  • Lymphotoxin — Lym|pho|toxi̱n [↑Lymphe u. ↑Toxin] s; s, e: von Lymphozyten gebildete Substanz, die Geschwulstzellen schädigt …   Das Wörterbuch medizinischer Fachausdrücke

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