MOWSE

MOWSE

MOlecular Weight SEarch (MOWSE) ist eine Methode um Proteine anhand der molaren Masse ihrer Peptide zu bestimmen, welche per Massenspektrometrie bestimmt wird.[1] Der Algorithmus MOWSE wurde von Darryl Pappin und David Perkins am Imperial Cancer Research Fund entwickelt und von Cancer Research Technology lizenziert. Der wahrscheinlichkeitsbasierte MOWSE-Score bildete die Basis für die Entwicklung von Mascot, einer Software für die Identifizierung von Proteinen anhand von Daten der Massenspektrometrie.

Einzelnachweise

  1. ↑ Pappin DJ, Hojrup P, Bleasby AJ: Rapid identification of proteins by peptide-mass fingerprinting. In: Curr. Biol.. 3, Nr. 6, Juni 1993, S. 327–32. doi:10.1016/0960-9822(93)90195-T. PMID 15335725.

Weblinks

  • Matrix Science Ltd: Scoring Schemes. In: www.matrixscience.com. 2010, abgerufen am 14. Juni 2011 (englisch, Dokumentation zum Verfahren).

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