Degranulation

Degranulation

Granula sind unter dem Mikroskop deutlich sichtbare, körnchenförmige Einlagerungen in biologischen Zellen, die meist Speicher- oder Sekretstoffe enthalten (z. B. Glykogen-, Lipid-, Protein-, Ferritin- oder Pigment-Granula). Sie lassen sich anhand ihrer Anfärbbarkeit in azidophil, azurophil, chromaffin, basophil, eosinophil, metachromatisch und neutrophil unterscheiden.

Die Freisetzung von Granula aus den Zellen nennt man Degranulation.


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  • Degranulation — The degranulation process in a Mast cell. 1 = antigen; 2 = IgE; 3 = FcεRI; 4 = preformed mediators (histamine, proteases, chemokines, heparin); 5 = granules; 6 Mast cell; 7 newly formed mediators (prostaglandins, leukotrienes, t …   Wikipedia

  • degranulation — noun Date: circa 1941 the process of losing granules; specifically the process by which cytoplasmic granules (as of mast cells) release their contents …   New Collegiate Dictionary

  • degranulation — Release of secretory granule contents by fusion with the plasma membrane …   Dictionary of molecular biology

  • degranulation — /dee gran yeuh lay sheuhn/, n. the loss or elimination of granules. [1940 45; DE + GRANULATION] * * * …   Universalium

  • degranulation — noun The loss of secretory granules in certain cells …   Wiktionary

  • degranulation — Disappearance or loss of cytoplasmic granules (lysosomes) from a cell. * * * de·gran·u·la·tion (.)dē .gran yə lā shən n the process of losing granules specif the process by which cytoplasmic granules (as of mast cells) release their contents… …   Medical dictionary

  • degranulation — de·granulation …   English syllables

  • dégranulation —  n.f. Biol. Processus de transformation des cellules …   Le dictionnaire des mots absents des autres dictionnaires

  • degranulation — (¦)dē, də̇ˌ noun Etymology: de + granulation : the process of losing granules ; specifically : the process by which cytoplasmic granules (as of mast cells) release their contents …   Useful english dictionary

  • basophil degranulation test — an in vitro procedure testing allergic sensitivity to a specific allergen at the cellular level by measuring staining of basophils after exposure to the allergen; a reduction in the number of granulated cells is a positive result …   Medical dictionary

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