High Power Field

High Power Field

Unter einem Hauptgesichtsfeld versteht man denjenigen Bereich, der bei insgesamt 400facher Vergrößerung unter dem Mikroskop zu sehen ist. Dies entspricht ungefähr einer Fläche von 5 mm², variiert aber von Mikroskop zu Mikroskop. Insbesondere bei sog. Weitfeldmikroskopen ist bezüglich der Vergleichbarkeit Vorsicht geboten.

Die Vergrößerung setzt sich aus der 40fachen Vergrößerung des Objektivs und der meist 10fachen Vergrößerung des Okulars zusammen. In der Wissenschaft ist die englische Bezeichnung High-Power-Field (Abkürzung HPF) dabei deutlich geläufiger.

Anwendung findet dieser Begriff z. B. in der Befundung histologischer Schnitte, z. B. 10 Mitosen auf 50 Hauptgesichtsfelder. Hierzu wird ein Hauptgesichtsfeld eingestellt, alle Mitosen gezählt und das Präparat zum nächsten HPF verschoben. Nun beginnt der Vorgang von neuem bis 50 HPF ausgezählt sind. Die Anzahl der Mitosen liefert dann einen Hinweis auf die Bösartigkeit mancher Krebsarten wie beispielsweise Gastrointestinaler Stromatumoren.[1]

Quellen

  1. Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O’Leary TJ, Remotti H, Rubin BP, Shmookler B, Sobin LH, Weiss SW.: Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 33: 459– 465 (2002)

Wikimedia Foundation.

Игры ⚽ Нужно сделать НИР?

Schlagen Sie auch in anderen Wörterbüchern nach:

  • High Power Field — (HPF) when used in relation to microscopy references the area visible under the maximum magnification power of the objective being used. Often, this represents a 400x magnification level when referenced in scientific papers …   Wikipedia

  • high-power field — the area of a slide visible under the high magnification system of a microscope …   Medical dictionary

  • High Power Electric Propulsion — (HiPEP) is a variation of ion thruster. It was ground tested in 2003 by NASA and intended for use on the Jupiter Icy Moons Orbiter, which was canceled in 2005. Theory The HiPEP thruster differs from earlier ion thrusters because the xenon ions… …   Wikipedia

  • National High Magnetic Field Laboratory — logo the National High Magnetic Field Laboratory (NHMFL) is a laboratory at Florida State University, with branches in University of Florida and at Los Alamos National Laboratory. NHMFL develops and research at magnetic fields for research in… …   Wikipedia

  • Field Target — is an outdoor air gun discipline originating in the United Kingdom, on the late 1980s, but gaining popularity worldwide.UK RulesIn UK (United Kingdom) rules, competitors aim to shoot the small “kill” zone that forms part of a larger metal… …   Wikipedia

  • Power engineering — Power engineering, also called power systems engineering, is a subfield of electrical engineering that deals with the generation, transmission and distribution of electric power as well as the electrical devices connected to such systems… …   Wikipedia

  • Power optimization (EDA) — Power optimization refers to the use of electronic design automation tools to optimize (reduce) the power consumption of a digital design, while preserving the functionality.Introduction and historyThe increasing speed and complexity of today’s… …   Wikipedia

  • Field emission — (FE) is the emission of electrons from the surface of a condensed phase into another phase due to the presence of high electric fields. In this phenomenon, electrons with energies below the Fermi level tunnel through the potential barrier at the… …   Wikipedia

  • Field electron emission — It is requested that a diagram or diagrams be included in this article to improve its quality. For more information, refer to discussion on this page and/or the listing at Wikipedia:Requested images. Field emission (FE) (also known as field… …   Wikipedia

  • Field emission display — A field emission display (FED) is a display technology that incorporates flat panel display technology that uses large area field electron emission sources to provide electrons that strike colored phosphor to produce a color image as a electronic …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”