Non-coding RNA

Non-coding RNA

Non-coding RNA (deutsch nicht-kodierende RNA, ncRNA) ist eine zusammenfassende Bezeichnung für Ribonukleinsäuren, die nicht wie die mRNA in Proteine übersetzt werden. Darunter fallen zum Beispiel rRNAs, tRNAs, kleine RNAs (miRNAs, siRNAs, piRNAs), antisense RNAs, Riboswitchs und Ribozyme. Non-coding RNA macht bei Eukaryoten den größten Teil der durch Transkription gebildeten RNA aus, beim Menschen z.B. 98 %.[1] Sie haben vielfältige Funktionen in der Zelle.[2]

Literatur

Siehe auch

Einzelnachweise

  1. ↑ John S. Mattick: Non-coding RNAs: the architects of eukaryotic complexity. In: EMBO reports 2, 11, 986–991 (2001). doi:10.1093/embo-reports/kve230
  2. ↑ Witzany, G. (2009). Noncoding RNAs: Persistent Viral Agents as Modular Tools for Cellular Needs. Ann NY Acad Sci 1178, 244-267.

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