Core (Protein)

Core (Protein)

Als Core (engl. Kern) bezeichnet bei Viruspartikeln eine innere Struktur bestehend aus Strukturproteinen und Genom. Beispiel[1]: Rotaviren; die Strukturproteine VP1 und VP3 bilden zusammen mit den 11 dsRNA (ds= double strand oder Doppelstrang) Genomsegmenten das innere Core welches vom VP2 Strukturprotein umgeben ist. Das VP2 formt somit die Core-Schale. Weiterhin ist das Rotavirus von einem inneren Capsid (VP6) und einem äußeren Capsid (VP4 und VP7) umgeben.[2]

Einzelnachweise

  1. ↑ Modrow, S., Falke, D., Truyen, U., Hermann, S., 2010, Molekulare Virologie, Spektrum Verlag, 3. Auflage
  2. ↑ Juana Angel, Manuel A. Franco & Harry B. Greenberg, Rotavirus vaccines: recent developments and future considerations, Nature Reviews Microbiology 5, 529-539 (July 2007)

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