Uroporphyrinogen-III-Synthase
- Uroporphyrinogen-III-Synthase
-
Die Uroporphyrinogen-III-Synthase (URO3S) ist das Enzym in Tieren, das den Ringschluss von Hydroxymethylbilan zu Uroporphyrinogen III katalysiert, ein Teilschritt in der Porphyrinbiosynthese. Im Mensch ist URO3S in allen Gewebetypen zu finden. Mutationen im UROS-Gen können zu URO3S-Mangel und dieser zu Morbus Günther führen.[2]
Katalysierte Reaktion
⇒ 
Hydroxymethylbilan cyclisiert zu Uroporphyrinogen III.
Einzelnachweise
- ↑ Homologe bei OMA
- ↑ UniProt P10746
Weblinks
Wikimedia Foundation.
Schlagen Sie auch in anderen Wörterbüchern nach:
Uroporphyrinogen III synthase — protein Name = uroporphyrinogen III synthase caption = width = HGNCid = 12592 Symbol = UROS AltSymbols = EntrezGene = 7390 OMIM = 606938 RefSeq = NM 000375 UniProt = P10746 PDB = ECnumber = 4.2.1.75 Chromosome = 10 Arm = q Band = 25.2 26.3… … Wikipedia
uroporphyrinogen-III synthase — uro·por·phy·rin·o·gen III syn·thase (u″ro por″fə rinґə jən sinґthās) [EC 4.2.1.75] an enzyme of the lyase class that acts concertedly with hydroxymethylbilane synthase to convert porphobilinogen to uroporphyrinogen … Medical dictionary
Uroporphyrinogen III — Chembox new ImageFile=Uroporphyrinogen III skeletal.svg ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=1976 85 8 PubChem=1179 SMILES= MeSHName=Uroporphyrinogen+III Section2= Chembox Properties Formula=C40H44N4O16… … Wikipedia
uroporphyrinogen III cosynthase — uro·por·phy·rin·o·gen III co·syn·thase (u″ro por″fə rinґə jən ko sinґthās) uroporphyrinogen III synthase … Medical dictionary
Uroporphyrinogen — Uroporphyrinogens are tetrapyrroles with four propionic acid groups and four acetic acid groups.There are four forms, which vary based upon the arrangements of the groups ( P ) and ( A ): * In the I variety, clockwise, the order repeats four… … Wikipedia
Coproporphyrinogen III oxidase — Coproporphyrinogen oxidase PDB rendering based on 2aex … Wikipedia
Cystathionine beta synthase — Structure of human cystathionine beta synthase.[1] … Wikipedia
Porphobilinogen synthase — Identifiers EC number 4.2.1.24 CAS number 9036 37 7 … Wikipedia
hydroxymethylbilane synthase — hy·droxy·meth·yl·bil·ane syn·thase (hi drok″se meth″əl bilґān sinґthās) [EC 2.5.1.61] an enzyme of the transferase class that catalyzes the deamination and condensation of four molecules of porphobilinogen to form a… … Medical dictionary
Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… … Wikipedia
Wikibooks: Biochemie und Pathobiochemie: Porphyrinbiosynthese – Lern- und Lehrmaterialien
