Donald S. Fredrickson

Donald S. Fredrickson, 1961

Donald S. Fredrickson (* 8. August 1924 in Cañon City; † 7. Juni 2002 in Bethesda, Maryland^[1]) war Physiologe und beschrieb 1961 als erster die Tangier-Krankheit.^[2] Neben zahlreichen anderen herausragenden Funktionen hatte er von 1975 bis 1981 das Amt des Direktors der National Institutes of Health (NIH) inne.^[3] 1978 wurde er mit einem Gairdner Foundation International Award ausgezeichnet. Nach ihm ist auch die Einteilung der Primären Hyperlipoproteinämien benannt.

Wesentliche Veröffentlichungen

Seine wesentlichen Veröffentlichungen fanden im Bereich des menschlichen Fettstoffwechsels und der Erbkrankheiten statt.^[4]

1. Hoffman, Harry N., and Donald S. Fredrickson. "Tangier Disease (Familial High Density Lipoprotein Deficiency): Clinical and Genetic Features in Two Adults." The American Journal of Medicine 39, 4 (Oktober 1965): 582-593.
2. Personal reminiscence of President Lyndon B. Johnson's 1965 visit to NIH.
3. Named Director of Heart Institute." NIH Record XVIII, 23 (15. November 1966): 1,4.
4. "Lipoprotein Patterns and Atherosclerosis." Lecture Notes. Program. 10 Images. 1966-1974.
5. "The Ultimate Operation." Time, (15. Dezember 1967): 64-72.
6. Description of the photograph of the conference on cardiac transplantation with Christiaan Barnard.
7. Fredrickson, Donald S., Robert I. Levy, and Robert S. Lees. "Fat Transport in Lipoproteins--An Integrated Approach to Mechanisms and Disorders." New England Journal of Medicine, (1967): 1-46.
8. Personal reminiscence of President Lyndon B. Johnson's 1967 visit to NIH.
9. Pruitt, John. "Tangier Disease: Tonsils May Cure Hearts." Virginian- Pilot, (1967).
10. "Dr. Donald S. Fredrickson Named Heart Institute's Director Intramural Research." NIH Record XXI, 6 (18. März 1969): 1,8.
11. Fleischmajer, Raul, and Alan M. Schragger. "Familial Hyperlipoproteinemias." Hahnemann University, After 1969. Report.
12. Fredrickson, Donald S., Edwin S. Bierman, David H. Blankenhorn, William Castelli, William E. Connor, Gerald R. Cooper, Seymour Dayton, Howard Eder, Ivan D. Frantz, William Friedewald, DeWitt S. Goodman, Frederick T. Hatch, Richard J. Havel, Peter Kuo, Robert S. Lees, Robert I. Levy, Robert P. Noble, Isidore Rosenfeld, Daniel Steinberg, and Theodore Cooper. "Report of the National Heart and Lung Institute Panel on Hyperlipidemia and Premature Atherosclerosis."
13. "Killer 'We Must Arrest at Once'." Christchurch Star, (27. September 1971)
14. Clifton-Bligh, P., P. J. Nestel, and H. M. Whyte. "Tangier Disease: Report of a Case and Studies of Lipid Metabolism." New England Journal of Medicine 286, 11 (16. März 1972): 567-571.
15. "Chanock and Fredrickson Elected NAS Members; Ceremony in April 1974." NIH Record XXV, 10 (8. Mai 1973): 1,3.
16. "Dr. Fredrickson to Head Institute of Medicine; Succeeds Dr. Hogness." NIH Record XXVI, 4 (12. Februar 1974): 1,6. Article.
17. Excerpts from Donald Fredrickson's inaugural speech as President of the Institute of Medicine.
18. "Tonsils and Apolipoproteins: Lessons about Plasma Lipoproteins Derived from Tangier Disease and Other Mutants." Jimenez Diaz Memorial Lectures, 1969-1974. Foundation Conchita Rabago, 1974. pp. 129–156.
19. 2Phenotyping: On Reaching Base Camp (1950-1975)." Circulation (Supplement) 87, 4 (April 1993): III-1-III-15.
20. "The First Heart Transplant in Man." Diary. Excerpt. Memoir. 26. April 1997.

Einzelnachweise

1. ↑ Profiles in Science: The Donald S. Fredrickson Papers - Biographical Information, hier online
2. ↑ Hoffman, Harry N., and Donald S. Fredrickson: Tangier Disease (Familial High Density Lipoprotein Deficiency): Clinical and Genetic Features in Two Adults.. In: The American Journal of Medicine 39, 4 (October 1965): 582-593; pdf
3. ↑ Profiles in Science: The Donald S. Fredrickson Papers - NIH Director, 1975-1981: Biomedical Research in a Time of Trial, hier online
4. ↑ Profiles in Science: The Donald S. Fredrickson Papers - Lipid Metabolism and Genetic Disease, 1953-1974: Documents, hier online