Growth-arrest-specific gene-6

Growth-arrest-specific gene-6
Growth-arrest-specific gene-6

Masse/Länge Primärstruktur 691 Aminosäuren
Sekundär- bis Quartärstruktur Heterodimer/-tetramer
Kofaktor Ca2+, AXL
Isoformen 3
Bezeichner
Gen-Name GAS6
Externe IDs OMIM600441 UniProtQ14393
Vorkommen
Homologie-Familie GAS6/Protein S
Übergeordnetes Taxon Euteleostomi

"Growth-arrest-specific gene-6" (oder kurz: "Gas6" genannt) ist ein Vitamin K-abhängiges Protein, welches in γ-carboxylierter Form an verschiedene Rezeptoren bindet, zum Beispiel an Rezeptor-Tyrosinkinasen. Es beeinflusst so Zellwachstum und Replikation. Die exakte Funktion von Gas6 ist noch nicht definiert, man denkt aber, dass es ein physiologisches antientzündliches Protein ist.

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